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Dr Usman Javaid
Dr Usman Javaid
Gastroenterologist
General Adult Medicine

Unexplained Weight Loss — treatment in Lahore

Also known as: Cachexia · Involuntary Weight Loss

Unintentional weight loss of more than 5% of body weight over 6–12 months without effort is a red-flag symptom that warrants comprehensive evaluation — from thyroid and diabetes to GI disease, malignancy, and chronic infection.

Dr Usman Javaid
Medically reviewed
Dr Usman Javaid · MPH, FRSPH (UK)
Last reviewed
Evidence-based

Overview

Unintentional weight loss is a red-flag symptom. A structured work-up — thyroid, diabetes, GI, infection, malignancy — finds the cause in most patients.

Signs & symptoms of Unexplained Weight Loss

If you recognize one or more of these, it may be worth a consultation:

  • Loss of >5% body weight in 6–12 months without effort
  • Reduced appetite
  • Night sweats or fevers
  • Any other persistent symptom

Causes & risk factors

Several factors can contribute to Unexplained Weight Loss. Identifying yours guides the treatment plan.

  • Hyperthyroidism
  • New-onset diabetes
  • Malabsorption (celiac, IBD, pancreatic insufficiency)
  • Chronic infection (TB, hepatitis, HIV)
  • Malignancy
  • Depression
  • Medication side effects
  • Substance use

How Unexplained Weight Loss is diagnosed

We order tests selectively — only what changes the plan.

  • Comprehensive bloodwork
  • Thyroid function, HbA1c
  • Chest X-ray and abdominal ultrasound
  • Endoscopy or colonoscopy when indicated

Treatment options

Treatment for Unexplained Weight Loss is personalized — the right plan depends on your symptoms, test results, and life situation.

  1. 1 Structured workup
  2. 2 Treat identified cause
  3. 3 Nutritional support

When should you see a doctor about Unexplained Weight Loss?

Reach out without delay if you notice any of the following.

  • Loss of >5% body weight in 6–12 months without trying
  • Loss of appetite
  • Night sweats
  • Fevers
  • Any persistent new symptom
Dr Usman Javaid
Author & medical reviewer

Dr Usman Javaid

Gastroenterology & Medicine Diplomat · DIP (Gastro) UK · DIP (Hepatology) UK · DIP (Diabetes) UK · MCPS FM-TC · MPH · FRSPH (UK) · FRCP (Colombo) · Organ Transplant Advisor · CHPE (NUMS) · Preventive Medicine Specialist · Owner of Javaid Poly Clinic.

This page was medically reviewed by Dr Usman Javaid on . Content is updated when new evidence or guidelines emerge.

Medical disclaimer: This page is for educational purposes and does not replace medical consultation. If you have symptoms of Unexplained Weight Loss or any other condition, please book a consultation. In emergencies, call 1122 or visit your nearest emergency department.

A clear plan starts with a careful conversation.

If something feels off — pain, reflux, fatigue, jaundice, weight change — don't wait it out alone. Book a consultation and let's understand it together.

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